The Biotherapies and Bioproduction of Innovative Therapies (BBTI) Research Program (PEPR), launched by the French government in 2021, is one of the major initiatives in the Biotherapies and Bioproduction of Innovative Therapies acceleration strategy of the France 2030 plan.
This research program, whose scientific management has been entrusted to Inserm and CEA, aims to contribute to the development of tomorrow’s biotherapies and associated key technologies.
It also aims to federate the national academic research ecosystem and promotes close links with industry and hospitals.
The PEPR is part of a wider drive to consolidate France’s leadership and competitiveness in this sector research and manufacturing processes.
Latest news
Call for applications – Support for Master 2 internship
Opening: January 1, 2026 – Closing: November 24, 2026
Call for applications – Participation in training courses and e-learning
Opening: January 1, 2026 – Closing: November 24, 2026
Call for applications – Research stays for young researchers
Opening: January 1, 2026 – Closing: November 24, 2026
Projects
BACTER-EV-BOOSTER
Multidisciplinary approach to stimulate the bioproduction and engineering of Gram+ bacteria’s Extracellular Vesicles (EVs) for therapeutic applications to treat inflammation
Bioengineered Skin-France
Bioengineering of next-generation skin substitutes for cutaneous regeneration
BIOSCALE
Improving the whole chain of large scale AAV bioproduction through disruptive technologies
CARN
Development of biotherapies based on the local delivery of therapeutic RNAs by hybrid functionalized extracellular vesicles (EVs) for musculoskeletal regeneration
iPSC France
Genomic editing of stable universal pluripotent stem cells for allogeneic cell biotherapies
QualAAV
Innovative approaches for quality control to support the industrial deployment of future gene therapy products.
STROMAEV
From engineering of iPS-derived mesenchymal stromal cell-derived extracellular vesicles to clinical translation
